Article
Weight is an independent predictor of vascular injury in healthy volunteers with aspartate allele.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 May 2012
Paradossi Umberto, Manfrini Olivia, Ciofini Enrica, Pizzi Carmine, Biagini Andrea, Xhyheri Borejda, Colombo Maria G
Abstract excerpt
BACKGROUND: Endothelial dysfunction and carotid intima-media thickeness (IMT) are currently considered key early events in atherogenesis and markers of arterial damage. We investigated whether endothelial nitric oxide synthase (eNOS) glutamate (Glu)298-aspartate (Asp) polymorphism may influence the vascular response to weight, as measured by BMI, in young, healthy individuals. METHODS: One hundred young...
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