Article
Low HDL cholesterol and the eNOS Glu298Asp polymorphism are associated with inducible myocardial ischemia in patients with suspected stable coronary artery disease.
BMC cardiovascular disorders - 22 Mar 2024
Vecoli Cecilia, Caselli Chiara, Modena Martina, Todiere Giancarlo, Poddighe Rosa, Valente Serafina, Bandini Fabrizio, Natali Andrea, Ghiadoni Lorenzo, Clerico Aldo, Prontera Concetta, Vittorini Simona, Botto Nicoletta, Emdin Michele, Neglia Danilo
Abstract excerpt
BACKGROUND: The endothelial nitric oxide synthase (eNOS) gene deficiency is known to cause impaired coronary vasodilating capability in animal models. In the general clinical population, the eNOS gene polymorphisms, able to affect eNOS activity, were associated with cardiometabolic risk features and prevalence of coronary artery disease (CAD). AIM: To investigate the association of eNOS Glu298Asp gene...
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