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Article

Endothelial nitric oxide synthase Glu(298)-->Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample.

Clinical science (London, England : 1979) - 1 Nov 2005

Wolff Birger, Braun Claudia, Schlüter Christina, Grabe Hans J, Popowski Katrin, Völzke Henry, Lüdemann Jan, John Ulrich, Cascorbi Ingolf

Abstract excerpt

The Glu(298)-->Asp (E298D; 894G-->T) polymorphism of eNOS (endothelial nitric oxide synthase) has been related with cardiovascular disease. In the present study, we investigated the association of Glu(298)-->Asp with atherosclerotic plaques in different carotid vessel segments and with carotid IMT (intima-media thickness). The Glu(298)-->Asp eNOS polymorphism was determined by 5'-exonuclease assay among 2448...

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Identifiers

PMID: 16060860
DOI: 10.1042/CS20050090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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