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Article

Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment.

Toxicology letters - 20 May 2012

Liu Xiaoshan, Lee Jinyoung, Ji Kyunghee, Takeda Shunichi, Choi Kyungho

Abstract excerpt

Genotoxic potentials and the mechanisms of six pharmaceuticals, which are frequently detected in surface water worldwide, were investigated using isogenic chicken DT40 mutant cell lines. These pharmaceuticals include erythromycin, sulfamethazine, sulfathiazole, chlortetracycline, oxytetracycline, and diclofenac. The genotoxic effects of these pharmaceuticals were determined based on growth kinetics of several...

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PMID: 22450446
DOI: 10.1016/j.toxlet.2012.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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