Antimutagenic evaluation of vitamins B1, B6 and B12 in vitro and in vivo, with the Ames test.

doi:10.1016/j.fct.2012.11.028

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Antimutagenic evaluation of vitamins B1, B6 and B12 in vitro and in vivo, with the Ames test.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Mar 2013

Arriaga-Alba Myriam, Ruiz-Pérez Nancy Janett, Sánchez-Navarrete Jaime, de Angel Beatriz López, Flores-Lozada Jorge, Blasco José Luis

Abstract excerpt

The aim of this work is to evaluate vitamins B antimutagenic effect against alkylatings methyl-N-nitro-N-nitrosoguanidine (MNNG), ethyl-N-nitro-N'- nitrosoguanidine (ENNG), frameshift mutagens 2-aminoanthracene (2AA) and 2-acetyl-amino-fluorene (2AF) and ROS-generating antibiotics norfloxacin (NOR) and nalidixic acid (NLX), using the in vitro Ames test. In vivo antimutagenesis studies were performed against...

Topics

2-Acetylaminofluorene
Animals
Anthracenes
Antimutagenic Agents
DNA Damage
Methylnitronitrosoguanidine
Mice
Mice, Inbred Strains
Mutagenicity Tests
Mutagens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Norfloxacin

Salmonella typhimurium

Thiamine

Vitamin B 12

Vitamin B 6

Source

Open in PubMed

Identifiers

PMID: 23201371
DOI: 10.1016/j.fct.2012.11.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antimutagenic evaluation of vitamins B1, B6 and B12 in vitro and in vivo, with the Ames test.PMID 23201371Read ↗

Genotoxicity guidelines recommended by International Conference of Harmonization (ICH).Semantic proximity Read ↗

Carcinogens and DNA damageSemantic proximity Read ↗

[Natural anti-mutagenic and anti-carcinogenic substances].Semantic proximity Read ↗

[Progress of the micronucleus test in the field of molecular cancer epidemiology].Semantic proximity Read ↗

Current trends and perspectives in nutrition and cancer prevention.Semantic proximity Read ↗

Antimutagenic and anticancer activity of Darjeeling tea in multiple test systems.Semantic proximity Read ↗

[Genotoxicity tests as a safety study required for the development of pharmaceuticals].Semantic proximity Read ↗

Protective properties of five newly synthesized cyclic compounds against sodium azide and N-methyl-N'-nitro-N-nitrosoguanidine genotoxicity.Semantic proximity Read ↗

Assessment of antimutagenicity and anticarcinogenicity.Semantic proximity Read ↗

Safety evaluation of vitamin K2 (menaquinone-7) via toxicological tests.Semantic proximity Read ↗

Terminalia arjuna, a herbal remedy against environmental carcinogenicity: An in vitro and in vivo studySemantic proximity Read ↗

Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.