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Comprehensive investigation of the mutagenic potential of six pesticides classified by IARC as probably carcinogenic to humans.

Chemosphere - 1 Aug 2024

Martinek Regina, Lózsa Rita, Póti Ádám, Németh Eszter, Várady György, Szabó Pál, Szüts Dávid

Abstract excerpt

Pesticides are significant environmental pollutants, and many of them possess mutagenic potential, which is closely linked to carcinogenesis. Here we tested the mutagenicity of all six pesticides classified probably carcinogenic (Group 2A) by the International Agency of Research on Cancer: 4,4'-DDT, captafol, dieldrin, diazinon, glyphosate and malathion. Whole genome sequencing of TK6 human lymphoblastoid cell...

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PMID: 38936485
DOI: 10.1016/j.chemosphere.2024.142700

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