Protective properties of five newly synthesized cyclic compounds against sodium azide and N-methyl-N'-nitro-N-nitrosoguanidine genotoxicity.

doi:10.1177/0748233711416954

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Article

Protective properties of five newly synthesized cyclic compounds against sodium azide and N-methyl-N'-nitro-N-nitrosoguanidine genotoxicity.

Toxicology and industrial health - 1 Aug 2012

Turhan Kadir, Ozturkcan S Arda, Turgut Zuhal, Karadayi Mehmet, Gulluce Medine

Abstract excerpt

The current study aims to determine the antimutagenic potential of five newly synthesized cyclic compounds against the genotoxic agents sodium azide (NaN₃) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). The mutant bacterial tester strains were NaN₃-sensitive Salmonella typhimurium TA1535 and MNNG-sensitive Escherichia coli WP2uvrA. According to the results, all the test compounds showed significant...

Topics

Analysis of Variance
Antimutagenic Agents
Escherichia coli
Heterocyclic Compounds
Methylnitronitrosoguanidine
Mutagenicity Tests
Mutagens
Mutation
Salmonella typhimurium
Sodium Azide

Source

Open in PubMed

Identifiers

PMID: 21967842
DOI: 10.1177/0748233711416954

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