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Article

Geft is dispensable for the development of the second heart field.

BMB reports - 1 Mar 2012

Fan Xiongwei, Hou Ning, Fan Kaiji, Yuan Jiajia, Mo Xiaoyang, Deng Yun, Wan Yongqi, Teng Yan, Yang Xiao, Wu Xiushan

Abstract excerpt

Geft is a guanine nucleotide exchange factor, which can specifically activate Rho family of small GTPase by catalyzing the exchange of bound GDP for GTP. Geft is highly expressed in the excitable tissue as heart and skeletal muscle and plays important roles in many cellular processes, such as cell proliferation, migration, and cell fate decision. However, the in vivo role of Geft remains unknown. Here, we...

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Identifiers

PMID: 22449701
DOI: 10.5483/bmbrep.2012.45.3.153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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