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Article

Math5 defines the ganglion cell competence state in a subpopulation of retinal progenitor cells exiting the cell cycle.

Developmental biology - 15 May 2012

Brzezinski Joseph A, Prasov Lev, Glaser Tom

Abstract excerpt

The basic helix-loop-helix (bHLH) transcription factor Math5 (Atoh7) is transiently expressed during early retinal histogenesis and is necessary for retinal ganglion cell (RGC) development. Using nucleoside pulse-chase experiments and clonal analysis, we determined that progenitor cells activate Math5 during or after the terminal division, with progressively later onset as histogenesis proceeds. We have traced...

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Identifiers

PMID: 22445509
DOI: 10.1016/j.ydbio.2012.03.006
PMCID: PMC3337348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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