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Article

Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog.

Neuron - 1 Jun 2001

Kay J N, Finger-Baier K C, Roeser T, Staub W, Baier H

Abstract excerpt

Mutation of the zebrafish lakritz (lak) locus completely eliminates the earliest-born retinal cells, the ganglion cells (RGCs). Instead, excess amacrine, bipolar, and Müller glial cells are generated in the mutant. The extra amacrines are found at ectopic locations in the ganglion cell layer. Cone photoreceptors appear unaffected by the mutation. Molecular analysis reveals that lak encodes Ath5, the zebrafish...

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Identifiers

PMID: 11430806
DOI: 10.1016/s0896-6273(01)00312-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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