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Article

Math5 is required for retinal ganglion cell and optic nerve formation.

Development (Cambridge, England) - 1 Jul 2001

Brown N L, Patel S, Brzezinski J, Glaser T

Abstract excerpt

The vertebrate retina contains seven major neuronal and glial cell types in an interconnected network that collects, processes and sends visual signals through the optic nerve to the brain. Retinal neuron differentiation is thought to require both intrinsic and extrinsic factors, yet few intrinsic gene products have been identified that direct this process. Math5 (Atoh7) encodes a basic helix-loop-helix (bHLH)...

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Identifiers

PMID: 11493566
DOI: 10.1242/dev.128.13.2497
PMCID: PMC1480839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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