Article
Anti-GSTT1 antibodies and Null genotype correlate with histological changes of antibody mediated rejection in kidney transplantation.
Transplant immunology - 1 Dec 2023
Obrișcă Bogdan, Leca Nicolae, Chou-Wu Elaine, Sibulesky Lena, Bakthavatsalam Ramasamy, Kling Catherine E, Alawieh Rasha, Smith Kelly D, Ismail Gener, Gimferrer Idoia
Abstract excerpt
BACKGROUND: The presence of anti-Glutathione S-transferase T1 (GSTT1) antibodies (abs) has been hypothesized as a pathogenic contributor in antibody-mediated rejection (AMR). METHODS: We aimed to evaluate the relationship between genetic variants of GSTT1, anti-GSTT1 abs and AMR in a cohort of 87 kidney transplant (KTx) patients using Immucor's non-HLA Luminex assay. Patients were classified according to...
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