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Article

Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.

PloS one - 1 Jan 2012

Budulac Simona E, Vonk Judith M, Postma Dirkje S, Siedlinski Mateusz, Timens Wim, Boezen Marike H

Abstract excerpt

Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function decline, and if these potential associations are independent of each other. The SNPs rs569207, rs1051730 and rs8034191 in...

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Source

Open in PubMed Open full text

Identifiers

PMID: 22438921
DOI: 10.1371/journal.pone.0033386
PMCID: PMC3305325

Genes

FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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