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Article

A SNP in G6PC2 predicts insulin secretion in type 1 diabetes.

Acta diabetologica - 1 Jun 2013

Sanda Srinath, Wei Shan, Rue Tessa, Shilling Heather, Greenbaum Carla

Abstract excerpt

We investigated whether single nucleotide polymorphisms in genes related to glucose metabolism correlate with insulin secretion in type 1 diabetes patients. A cohort of 49 type 1 diabetes patients underwent serial mixed meal tolerance tests to assess insulin secretion. Patients were genotyped for SNPs related to glucose metabolism: CDKAL1 rs7754840, G6PC2 rs560887, HHEX rs1111875, KCNJ11 rs5215. Recently...

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Topics

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Share to Cyclin-Dependent Kinase 5
Share to Diabetes Mellitus, Type 1
Share to Glucose-6-Phosphatase
Share to Insulin
Share to Insulin Secretion
Share to Potassium Channels, Inwardly Rectifying
Share to Predictive Value of Tests
Share to tRNA Methyltransferases

Source

Identifiers

PMID: 22438186
DOI: 10.1007/s00592-012-0389-y

Genes

CDKAL1
HHEX
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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