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Article

Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury.

The Journal of pathology - 1 Sept 2012

Kasperkiewicz Michael, Nimmerjahn Falk, Wende Sabina, Hirose Misa, Iwata Hiroaki, Jonkman Marcel F, Samavedam Unni, Gupta Yask, Möller Steffen, Rentz Ellen, Hellberg Lars, Kalies Kathrin, Yu Xinhua, Schmidt Enno, Häsler Robert, Laskay Tamás, Westermann Jürgen, Köhl Jörg, Zillikens Detlef, Ludwig Ralf J

Abstract excerpt

Autoantibody-mediated diseases are clinically heterogeneous and often fail conventional therapeutic strategies. Gene expression profiling has helped to identify new molecular pathways in these diseases, although their potential as treatment targets largely remains to be functionally validated. Based on weighted gene co-expression network analysis, we determined the transcriptional network in experimental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22430937
DOI: 10.1002/path.4023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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