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Article

Opposing effects of Toll-like receptor stimulation induce autoimmunity or tolerance.

Trends in immunology - 1 Feb 2007

Ehlers Marc, Ravetch Jeffrey V

Abstract excerpt

Toll-like receptor (TLR) activation by pathogens can induce the activation of diverse cell populations of the immune system and, therefore, can initiate or augment protective T-helper 1 immune responses. However, on a susceptible genetic background, TLR stimulation can also induce autoimmunity. T...

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Source

Identifiers

PMID: 17197239
DOI: 10.1016/j.it.2006.12.006

Genes

TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17197239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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