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Programmed death 1 expressing CD8+CXCR5+ follicular T cells constitute effector rather than exhaustive phenotype in patients with chronic hepatitis B

24 Oct 2021

Abstract excerpt

Abstract Background and Aims Classical CD8 T cells are implicated for protective and pathogenic roles in chronic hepatitis B (CHB) infection. Recently, a subset of CD8 T cells expressing C‐X‐C chemokine receptor type 5 (CXCR5) and exhibiting features of T FH cells has been identified during chronic viral infections. However, in CHB, knowledge of their roles is limited. Approach and Results We characterized...

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PMID: 34689344
DOI: 10.1002/hep.32210

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