Article
Aminoglycosides: therapeutics, ototoxicity and hypersensitivity of mitochondrial genetic origin.
Proceedings of the Western Pharmacology Society - 1 Jan 2011
Torres-Ruíz N M, Granados O, Meza G
Abstract excerpt
Aminoglycosides such as streptomycin or gentamycin are employed to treat stubborn infections. In México, tuberculosis patients are successfully treated with 1 g/day for over 6 months. Ototoxicity is often seen as a consequence of prolonged treatment with aminoglycosides. In young people STP damages the vestibule of the ear; in elder patients it diminishes hearing and balance. These effects are due to streptidine,...
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