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Article

[The relation between mitochondrial DNA mutation and aminogly- coside antibiotics-induced deafness].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 1999

Zhang L, Lu M, Huang Y, Zhou X, Qiu D, Wang W

Abstract excerpt

OBJECTIVE: To nvestigate the relation between mitochondrial DNA mutation and aminoglycoside antibiotics-induced deafness. METHODS: Mitochondrial DNA (mtDNA) of peripheral blood from 48 sporadic cases was analysed using PCR-BsmAI digestion and PCR-direct DNA silver sequencing. RESULTS: Six of 48 sporadic patients had A to G mutation in 12S rRNA gene of mtDNA at nucleotide 1555. CONCLUSION: The results suggest that...

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Identifiers

PMID: 10359860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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