Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of aminoglycoside-induced and prelingual non-syndromic mitochondrial hearing impairment: a review.

International journal of audiology - 1 Nov 2008

Bindu L Hema, Reddy P P

Abstract excerpt

Pathogenic mitochondrial DNA mutations are most often implicated in inherited and acquired hearing impairment. The current review mainly focuses on the 12S rRNA mitochondrial gene mutations associated with non-syndromic deafness without or after aminoglycosides exposure. Aminoglycoside-induced and nonsyndromic deafness has been shown to have a genetic susceptibility and the pathogenic mitochondrial 12S rRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminoglycosides
Share to Anti-Bacterial Agents
Share to Genes, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, rRNA

Share to Hearing Loss

Share to Mutation

Share to RNA, Ribosomal

Source

Identifiers

PMID: 19031229
DOI: 10.1080/14992020802215862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of aminoglycoside-induced and prelingual non-syndromic mitochondrial hearing impairment: a review.PMID 19031229Read ↗

Mitochondrial 12S rRNA mutations associated with aminoglycoside ototoxicity.Semantic proximity Read ↗

Mitochondrial 12S rRNA variants in 1642 Han Chinese pediatric subjects with aminoglycoside-induced and nonsyndromic hearing loss.Semantic proximity Read ↗

[Mitochondrial DNA mutations and aminoglycoside antibiotics and hearing loss].Semantic proximity Read ↗

Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics.Semantic proximity Read ↗

Mitochondrial gene mutation is a significant predisposing factor in aminoglycoside ototoxicity.Semantic proximity Read ↗

Mitochondrial 12S rRNA A827G mutation is involved in the genetic susceptibility to aminoglycoside ototoxicity.Semantic proximity Read ↗

[Mitochondrial 12S rRNA variants studies in 456 subjects with hearing loss in seven schools for deaf and mutes in Zhejiang province].Semantic proximity Read ↗

Mutational analysis of the mitochondrial 12S rRNA gene in Chinese pediatric subjects with aminoglycoside-induced and non-syndromic hearing loss.Semantic proximity Read ↗

Maternally transmitted aminoglycoside-induced and non-syndromic hearing loss caused by the 1494C > T mutation in the mitochondrial 12S rRNA gene in two Chinese families.Semantic proximity Read ↗

The role of mitochondrial DNA mutations in hearing loss.Semantic proximity Read ↗

[Characterization of two Chinese families with aminoglycoside-induced and nonsyndromic hearing loss both carrying a mitochondrial 12S rRNA 1494C>T mutation].Semantic proximity Read ↗

Susceptibility mutations in the mitochondrial small ribosomal RNA gene in aminoglycoside induced deafness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.