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Article

A Molecular basis for human hypersensitivity of aminoglyscoside antibiotics

1 Jan 1993

Abstract excerpt

We have investigated the distribution of mitochondrial DNA polymorphisms in a rare maternally transmitted genetic trait that causes hypersensitivity to aminoglycoside antibiotics, in the hope that a characterization of its molecular basis might provide a molecular and cellular understanding of aminoglycoside-induced deafness (AGD). Here we report that the frequency of a particular mitochondrial DNA polymorphism,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8414970
DOI: 10.1093/nar/21.18.4174

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A Molecular basis for human hypersensitivity of aminoglyscoside antibioticsPMID 8414970Read ↗

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