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Article

Control of MCAK degradation and removal from centromeres.

Cytoskeleton (Hoboken, N.J.) - 1 May 2012

Ganguly Anutosh, Bhattacharya Rajat, Cabral Fernando

Abstract excerpt

Mitotic centromere associated kinesin (MCAK) is a kinesin related protein with the ability to stimulate microtubule depolymerization. It is found at spindle poles, where it may be involved in poleward microtubule flux, and at kinetochores and centromeres where it plays a role in correcting chromosome alignment errors. Its microtubule depolymerase activity and recruitment to centromeres is regulated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22422706
DOI: 10.1002/cm.21026
PMCID: PMC3390786

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