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Article

Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP).

Basic research in cardiology - 1 May 2012

Kuhn Christian, Frank Derk, Dierck Franziska, Oehl Ulrike, Krebs Jutta, Will Rainer, Lehmann Lorenz H, Backs Johannes, Katus Hugo A, Frey Norbert

Abstract excerpt

Muscle LIM protein (MLP) has been proposed to be a central player in the pathogenesis of heart muscle disease. In line with this notion, the homozygous loss of MLP results in cardiac hypertrophy and dilated cardiomyopathy. Moreover, MLP is induced in several models of cardiac hypertrophy such as aortic banding and myocardial infarction. We thus hypothesized that overexpression of MLP might change the hypertrophic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22421737
DOI: 10.1007/s00395-012-0262-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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