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Article

Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk.

The Journal of clinical endocrinology and metabolism - 1 May 2012

Sainz Juan, Rudolph Anja, Hoffmeister Michael, Frank Bernd, Brenner Hermann, Chang-Claude Jenny, Hemminki Kari, Försti Asta

Abstract excerpt

BACKGROUND: The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood. RESEARCH DESIGN AND METHODS: Given that the genetic background contributes to both traits, it is conceivable that genetic variants associated with T2D may also influence the...

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Identifiers

PMID: 22419714
DOI: 10.1210/jc.2011-2565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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