Article
Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study.
Diabetes care - 1 May 2008
Folsom Aaron R, Pankow James S, Peacock James M, Bielinski Suzette J, Heiss Gerardo, Boerwinkle Eric
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine whether a variation in the transcription factor 7-like 2 (TCF7L2) gene, which influences diabetes risk, is associated with incidence of cancers. RESEARCH DESIGN AND METHODS: We related diabetes and TCF7L2 variation with occurrence of several common cancers in a prospective cohort study of 13,117 middle-aged adults initially free of cancer in 1987-1989. We...
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