Young-onset colorectal cancer is associated with a personal history of type 2 diabetes.

doi:10.1111/ajco.13428

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Article

Young-onset colorectal cancer is associated with a personal history of type 2 diabetes.

Asia-Pacific journal of clinical oncology - 1 Feb 2021

Mikaeel Reger R, Symonds Erin L, Kimber James, Smith Eric, Horsnell Mehgan, Uylaki Wendy, Tapia Rico Gonzalo, Hewett Peter J, Yong Jonathan, Tonkin Darren, Jesudason David, Poplawski Nicola K, Ruszkiewicz Andrew R, Drew Paul A, Hardingham Jenny E, Wong Stephanie, Frank Oliver, Tomita Yoko, Patel Dainik, Vatandoust Sina, Townsend Amanda R, Roder David, Young Graeme P, Parry Susan, Tomlinson Ian P, Wittert Gary, Wattchow David, Worthley Daniel L, Brooks William J, Price Timothy J, Young Joanne P

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is rising in incidence in young adults, and this observation is currently unexplained. We investigated whether having a personal history of type 2 diabetes mellitus (T2D) was a potential risk factor for young-onset colorectal cancer (YOCRC). METHODS: The South Australian Young Onset (SAYO) CRC study is a series of young adults with CRC below age 55. Ninety unrelated YOCRC cases...

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PMID: 32885561
DOI: 10.1111/ajco.13428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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