Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of RAD51D in non-BRCA1/2 ovarian and breast cancer families.

British journal of cancer - 10 Apr 2012

Osher D J, De Leeneer K, Michils G, Hamel N, Tomiak E, Poppe B, Leunen K, Legius E, Shuen A, Smith E, Arseneau J, Tonin P, Matthijs G, Claes K, Tischkowitz M D, Foulkes W D

Abstract excerpt

BACKGROUND: Recent data show that mutations in RAD51D have an aetiological role in ovarian carcinoma, yet mutations do not appear to be associated with an increased risk for breast cancer. We studied ovarian and breast cancer families having at least one woman affected by ovarian carcinoma, to assess the importance of RAD51D mutations in such families. METHODS: The coding region of the RAD51D gene was analysed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to DNA-Binding Proteins

Share to DNA Mutational Analysis

Share to Genetic Testing

Share to Ovarian Neoplasms

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 22415235
DOI: 10.1038/bjc.2012.87
PMCID: PMC3326673

Genes

BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of RAD51D in non-BRCA1/2 ovarian and breast cancer families.PMID 22415235Read ↗

A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer.Semantic proximity Read ↗

Analysis of RAD51D in ovarian cancer patients and families with a history of ovarian or breast cancer.Semantic proximity Read ↗

A decade of RAD51C/D: Germline pathogenic variants and their phenotypic landscapeSemantic proximity Read ↗

A decade of RAD51C and RAD51D germline variants in cancer.Semantic proximity Read ↗

The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique PopulationSemantic proximity Read ↗

Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing.Semantic proximity Read ↗

Germline mutations in RAD51C and RAD51D and hereditary predisposition to ovarian cancer.Semantic proximity Read ↗

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.Semantic proximity Read ↗

Genetic testing for RAD51C mutations: in the clinic and community.Semantic proximity Read ↗

Germline mutations in RAD51D confer susceptibility to ovarian cancer.Semantic proximity Read ↗

Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.Semantic proximity Read ↗

Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.