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Article

Genetic testing for RAD51C mutations: in the clinic and community.

Clinical genetics - 1 Oct 2015

Sopik V, Akbari M R, Narod S A

Abstract excerpt

Much of the observed familial clustering of breast and ovarian cancer cannot be explained by mutations in BRCA1 and BRCA2. Several other cancer susceptibility genes have been identified, but their value in routine clinical genetic testing is still unclear. Germline mutations in RAD51C have been identified in about 1% of hereditary breast and ovarian cancer families. RAD51C mutations are predominantly found in...

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Source

Identifiers

PMID: 25470109
DOI: 10.1111/cge.12548

Genes

BRCA1
BRCA2

Provenance

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Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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