Article

Predicting Cognitive Decline in Early Alzheimer’s: Insights from East Asian Cohorts

2026-02-03

Abstract excerpt

<title>Abstract</title> <p> Background While cognitive decline is inevitable in early Alzheimer’s disease (AD) and amnestic mild cognitive impairment (aMCI), the rate of decline varies widely. Aims This study aimed to identify groups of individuals following similar trajectories of cognitive decline, and develop a model predicting those at risk of rapid decline. Methods A longitudinal study of 251 clinic-base...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5f371755-aaad-5597-95e3-ae41478d2e60
DOI: 10.21203/rs.3.rs-8629600/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting Cognitive Decline in Early Alzheimer’s: Insights from East Asian CohortsDOI 10.21203/rs.3.rs-8629600/v1Read

Identification of and a Prediction Model for Cognitive Trajectories in Patients With Mild Cognitive Impairment Due to Alzheimer’s DiseaseSemantic proximity Read

Predictive factors for disease progression in patients with early-onset Alzheimer's disease.Semantic proximity Read

Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study.Semantic proximity Read

Predicting Cognitive Decline across Four Decades in Mutation Carriers and Non-carriers in Autosomal-Dominant Alzheimer's Disease.Semantic proximity Read

Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study.Semantic proximity Read

Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing.Semantic proximity Read

Development and Validation of a Risk Prediction Model for Mild Cognitive Impairment in Older Chinese Adults with Chronic DiseasesSemantic proximity Read

Prognostic factors for the 6-year cognitive impairment in China: results from the CLHLS cohortSemantic proximity Read

APOE ε4 increases the risk of progression from amnestic mild cognitive impairment to Alzheimer's disease among ethnic Chinese in Taiwan.Semantic proximity Read

Pre-clinical cognitive phenotypes for Alzheimer disease: a latent profile approach.Semantic proximity Read

Risk factors and predictive models in the progression from MCI to Alzheimer’s diseaseSemantic proximity Read

Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study.Semantic proximity Read