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Article

Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response.

Journal of translational medicine - 13 Mar 2012

Turner Stephen T, Schwartz Gary L, Chapman Arlene B, Beitelshees Amber L, Gums John G, Cooper-Dehoff Rhonda M, Boerwinkle Eric, Johnson Julie A, Bailey Kent R

Abstract excerpt

BACKGROUND: To determine whether office, home, ambulatory daytime and nighttime blood pressure (BP) responses to antihypertensive drug therapy measure the same signal and which method provides greatest power to identify genetic predictors of BP response. METHODS: We analyzed office, home, ambulatory daytime and nighttime BP responses in hypertensive adults randomized to atenolol (N = 242) or hydrochlorothiazide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22413836
DOI: 10.1186/1479-5876-10-47
PMCID: PMC3342146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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