Article
Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala: lack of association with weight gain in psychiatric inpatients treated with olanzapine or clozapine.
Molecular diagnosis & therapy - 1 Apr 2012
Staeker Julia, Leucht Stefan, Steimer Werner
Abstract excerpt
BACKGROUND AND OBJECTIVE: Weight gain is a common problem of treatment with atypical antipsychotics. However, the dimension of body weight change differs interindividually, and various genetic factors are considered to be associated with this effect. Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism and its reported relationship to type 2 diabetes susceptibility and body mass...
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