Article
No evidence for a role of the peroxisome proliferator-activated receptor gamma (PPARG) and adiponectin (ADIPOQ) genes in antipsychotic-induced weight gain.
Psychiatry research - 30 Oct 2014
Brandl Eva J, Tiwari Arun K, Zai Clement C, Chowdhury Nabilah I, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L, Müller Daniel J
Abstract excerpt
Antipsychotics frequently cause changes in glucose metabolism followed by development of weight gain and/or diabetes. Recent findings from our group indicated an influence of glucose-related genes on this serious side effect. With this study, we aimed to extend previous research and performed a comprehensive study on the peroxisome proliferator-activated receptor gamma (PPARG) and the adiponectin (ADIPOQ) genes....
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