Article
Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain.
Human psychopharmacology - 1 Jan 2000
Park Young-Min, Choi Jung-Eun, Kang Seung-Gul, Koo Seung-Hoi, Kim Leen, Geum Dongho, Lee Heon-Jeong
Abstract excerpt
BACKGROUND: Olanzapine is an atypical antipsychotic known to cause considerable weight gain. The cannabinoid type 1 receptor has been reported to be involved in energy balance control, appetite stimulation, and increases in body weight. METHODS: In the present study, we investigated three polymorphisms (rs1049353, rs806368, and rs4707436) in the cannabinoid type 1 receptor gene (CNR1) and weight gain in Korean...
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