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Article

Role of an isoform-specific serine residue in FMN-heme electron transfer in inducible nitric oxide synthase.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Jun 2012

Li Wenbing, Fan Weihong, Chen Li, Elmore Bradley O, Piazza Mike, Guillemette J Guy, Feng Changjian

Abstract excerpt

In the crystal structure of a calmodulin (CaM)-bound FMN domain of human inducible nitric oxide synthase (NOS), the CaM-binding region together with CaM forms a hinge, and pivots on an R536(NOS)/E47(CaM) pair (Xia et al. J Biol Chem 284:30708-30717, 2009). Notably, isoform-specific human inducibl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22407542
DOI: 10.1007/s00775-012-0887-y
PMCID: PMC3526944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22407542-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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