Article
Impact of tumour necrosis factor-α polymorphisms on irritant contact dermatitis.
Contact dermatitis - 1 Apr 2012
Landeck Lilla, Visser Maaike, Kezic Sanja, John Swen M
Abstract excerpt
BACKGROUND: Genetic variations in genes coding for cytokines involved in skin inflammation may alter their expression, thus changing the susceptibility to irritant contact dermatitis (ICD). OBJECTIVES: To determine the prevalence of polymorphisms in the cytokine genes TNFA-238 and TNFA-308 in patients with occupational ICD, and to compare it with that in controls. METHODS: In a case-control study, 478 patients...
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