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Article

<i>IL1A</i>‐889 C/T gene polymorphism in irritant contact dermatitis

25 Feb 2012

Abstract excerpt

BACKGROUND: Upon skin contact to irritants, interleukin-1 alpha (IL-1α) is released in the stratum corneum as a primary step of skin inflammation. Variations in the IL-1A gene have been shown to alter the expression of IL-1α. This may influence the susceptibility to skin inflammation and the development of irritant contact dermatitis (ICD). OBJECTIVE: To determine effects of an IL1A-889 C/T polymorphism in view...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22364598
DOI: 10.1111/j.1468-3083.2012.04474.x

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