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Article

Tumor necrosis factor α-308 G/A and interleukin 1 β-511 C/T gene polymorphisms in patients with scarring acne.

Journal of cosmetic dermatology - 1 Feb 2019

Akoglu Gulsen, Tan Cagman, Ayvaz Deniz Cagdas, Tezcan Ilhan

Abstract excerpt

BACKGROUND: Acne is a chronic inflammatory skin disorder which may heal with scarring. Tumor necrosis factor alpha (TNF α) and interleukin 1 β (IL-1β) are considered as the main responsible proinflammatory mediators of acne pathogenesis. Oversecretion of these cytokines was found to be associated with TNF α-308 G>A and IL-1β-511 C<T polymorphisms. AIM: To evaluate the association of TNF α-308 and IL-1β-511 gene...

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PMID: 29675912
DOI: 10.1111/jocd.12558

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TNF

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