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Article

Association of TNFA gene polymorphism at position -308 with susceptibility to irritant contact dermatitis.

Immunogenetics - 1 Mar 2000

Allen M H, Wakelin S H, Holloway D, Lisby S, Baadsgaard O, Barker J N, McFadden J P

Abstract excerpt

Mechanisms underlying susceptibility to skin irritants are not clearly understood. Cytokines play a key role in inflammation, and functional polymorphisms in cytokine genes may affect responses to irritants. We investigated the relationship between polymorphism in the tumor necrosis factor (TNF) alpha-chain gene and responses to irritants. Volunteers (n=221) tested with sodium dodecyl sulfate (SDS) and...

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Source

Identifiers

PMID: 10752629
DOI: 10.1007/s002510050032

Genes

SDS
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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