Article
AmpliSeq Screening of Genes Encoding the C-Type Lectin Receptors and Their Signaling Components Reveals a Common Variant in MASP1 Associated with Pulmonary Tuberculosis in an Indian Population.
Frontiers in immunology - 1 Jan 2018
Klassert Tilman E, Goyal Surabhi, Stock Magdalena, Driesch Dominik, Hussain Abid, Berrocal-Almanza Luis Carlos, Myakala Rajashekar, Sumanlatha Gaddam, Valluri Vijayalakshmi, Ahmed Niyaz, Schumann Ralf R, Flores Carlos, Slevogt Hortense
Abstract excerpt
Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental factors. On the host side, growing evidence shows the crucial role that genetic variants play in the susceptibility to Mycobacterium tuberculosis (Mtb) infection. Such polymorphisms have been described in genes encoding for different cytokines and pattern recognition receptors (PRR), including numerous Toll-like receptors...
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