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Article

Common variants in the TPH2 promoter confer susceptibility to paranoid schizophrenia.

Journal of molecular neuroscience : MN - 1 Jul 2012

Yi Zhenghui, Zhang Chen, Lu Weihong, Song Lisheng, Liu Dentang, Xu Yifeng, Fang Yiru

Abstract excerpt

Serotonergic system-related genes may be good candidates in investigating the genetic basis of schizophrenia. Our previous study suggested that promoter region of tryptophan hydroxylase 2 gene (TPH2) may confer the susceptibility to paranoid schizophrenia. In this study, we investigated whether common variants within TPH2 promoter may predispose to paranoid schizophrenia in Han Chinese. A total of 509 patients...

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Source

Identifiers

PMID: 22392150
DOI: 10.1007/s12031-012-9725-5

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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