Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.

Development (Cambridge, England) - 1 Sept 2004

Das Gishnu, Jenny Andreas, Klein Thomas J, Eaton Suzanne, Mlodzik Marek

Abstract excerpt

Planar cell polarity (PCP) in the Drosophila eye is established by the distinct fate specifications of photoreceptors R3 and R4, and is regulated by the Frizzled (Fz)/PCP signaling pathway. Before the PCP proteins become asymmetrically localized to opposite poles of the cell in response to Fz/PCP signaling, they are uniformly apically colocalized. Little is known about how the apical localization is maintained....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Polarity
Share to Cell Size

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dishevelled Proteins

Share to Frizzled Receptors

Share to LIM Domain Proteins

Share to Phosphoproteins

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 15306567
DOI: 10.1242/dev.01317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.PMID 15306567Read ↗

The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye.Semantic proximity Read ↗

The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization.Semantic proximity Read ↗

Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding.Semantic proximity Read ↗

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling.Semantic proximity Read ↗

Novel regulators of planar cell polarity: a genetic analysis in Drosophila.Semantic proximity Read ↗

Flamingo, a seven-pass transmembrane cadherin, cooperates with Netrin/Frazzled in Drosophila midline guidance.Semantic proximity Read ↗

Planar polarity from flies to vertebrates.Semantic proximity Read ↗

The apical/basal-polarity determinant Scribble cooperates with the PCP core factor Stbm/Vang and functions as one of its effectors.Semantic proximity Read ↗

The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila.Semantic proximity Read ↗

Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning.Semantic proximity Read ↗

The planar cell polarity Vangl2 protein: From genetics to cellular and molecular functions.Semantic proximity Read ↗

Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.