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Article

Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila.

Molecular brain - 19 Apr 2011

Fernandes Caroline, Rao Yong

Abstract excerpt

BACKGROUND: Mutations in parkin and PTEN-induced kinase 1 (Pink1) lead to autosomal recessive forms of Parkinson's disease (PD). parkin and Pink1 encode a ubiquitin-protein ligase and a mitochondrially localized serine/threonine kinase, respectively. Recent studies have implicated Parkin and Pink1 in a common and evolutionarily conserved pathway for protecting mitochondrial integrity. RESULTS: To systematically...

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Source

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Identifiers

PMID: 21504582
DOI: 10.1186/1756-6606-4-17
PMCID: PMC3094290

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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