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Article

The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

Behavior genetics - 1 Jul 2012

Lubke Gitta H, Stephens Sarah H, Lessem Jeffrey M, Hewitt John K, Ehringer Marissa A

Abstract excerpt

Multiple studies have provided evidence for genetic associations between single nucleotide polymorphisms (SNPs) located on the CHRNA5/A3/B4 gene cluster and various phenotypes related to Nicotine Dependence (Greenbaum et al. 2009). Only a few studies have investigated other substances of abuse. The current study has two aims, (1) to extend previous findings by focusing on associations between the CHRNA5/A3/B4...

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Source

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Identifiers

PMID: 22382757
DOI: 10.1007/s10519-012-9529-y
PMCID: PMC3743232

Genes

CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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