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Article

A GABRA2 polymorphism improves a model for prediction of drinking initiation.

Alcohol (Fayetteville, N.Y.) - 1 Sept 2017

Kuperman Samuel, Chan Grace, Kramer John, Wetherill Leah, Acion Laura, Edenberg Howard J, Foroud Tatiana M, Nurnberger John, Agrawal Arpana, Anokhin Andrey, Brooks Andrew, Hesselbrock Victor, Hesselbrock Michie, Schuckit Marc, Tischfield Jay, Liu Xiangtao

Abstract excerpt

BACKGROUND: Survival analysis was used to explore the addition of a single nucleotide polymorphism (SNP) and covariates (sex, interview age, and ancestry) on a previously published model's ability to predict onset of drinking. A SNP variant of rs279871, in the chromosome 4 gene encoding gamma-aminobutyric acid receptor (GABRA2), was selected due to its associations with alcoholism in young adults and with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

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Share to Receptors, GABA-A

Source

Open in PubMed Open full text

Identifiers

PMID: 28847377
DOI: 10.1016/j.alcohol.2017.03.003
PMCID: PMC5657392

Genes

GABRA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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