Article
MAGI1 copy number variation in bipolar affective disorder and schizophrenia.
Biological psychiatry - 15 May 2012
Karlsson Robert, Graae Lisette, Lekman Magnus, Wang Dai, Favis Reyna, Axelsson Tomas, Galter Dagmar, Belin Andrea Carmine, Paddock Silvia
Abstract excerpt
BACKGROUND: Bipolar affective disorder (BPAD) and schizophrenia (SZ) are devastating psychiatric disorders that each affect about 1% of the population worldwide. Identification of new drug targets is an important step toward better treatment of these poorly understood diseases. METHODS: Genome-wide copy number variation (CNV) was assessed and variants were ranked by co-occurrence with disease in 48 BPAD families....
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