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Article

Copy number variation and psychiatric disease risk.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Levy Rebecca J, Xu Bin, Gogos Joseph A, Karayiorgou Maria

Abstract excerpt

Psychiatric disorders are multifactorial in nature with complex genetic architecture. A number of recent studies, building upon earlier findings of copy number variants (CNVs) at the 22q11.2 locus, suggest that rare CNVs represent an important component of genetic heterogeneity in the etiology of complex psychiatric diseases, such as schizophrenia. De novo CNVs are found with higher frequency among sporadic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22228008
DOI: 10.1007/978-1-61779-507-7_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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