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Article

GSTM1 null genotype as risk factor for late-onset Alzheimer's disease in Italian patients.

Journal of the neurological sciences - 15 Jun 2012

Piacentini Sara, Polimanti Renato, Squitti Rosanna, Ventriglia Mariacarla, Cassetta Emanuele, Vernieri Fabrizio, Rossini Paolo Maria, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia in the elderly. The causes of AD are very complex but there is general agreement about the existence of a link between Alzheimer's disease and oxidative stress. The Glutathione S-transferases (GSTs) act to detoxify products of oxidation that cause damage to macromolecules. Particular attention has been focused on GST genes because polymorphisms are...

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Source

Identifiers

PMID: 22381228
DOI: 10.1016/j.jns.2012.01.026

Genes

GSTM1
GSTA1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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