Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A preliminary study on the influence of glutathione S transferase T1 (GSTT1) as a risk factor for late onset Alzheimer's disease in North Indian population.

Asian journal of psychiatry - 1 Jun 2012

Ghosh Tandra, Mustafa Md, Kumar Vivek, Datta Sudip Kumar, Bhatia Manjit Singh, Sircar Sabyasachi, Banerjee Basu Dev

Abstract excerpt

INTRODUCTION: Oxidative stress plays key role in pathogenesis of Alzheimer's disease. Glutathione S-transferases (GSTs), a family of phase-II isoenzymes, play a critical role in providing protection against electrophiles and products of oxidative stress. Among different classes of GSTs, GSTM1 (Mu) and GSTT1 (theta) are found to be genetically deleted which results in decreased expression of the concerned enzyme....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Glutathione Transferase

Share to Polymorphism, Genetic

Share to Psychiatric Status Rating Scales

Share to Risk Factors

Source

Identifiers

PMID: 22813660
DOI: 10.1016/j.ajp.2012.02.023

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A preliminary study on the influence of glutathione S transferase T1 (GSTT1) as a risk factor for late onset Alzheimer's disease in North Indian population.PMID 22813660Read ↗

Association of glutathione S-transferases M1, P1 and T1 variations and risk of late-onset Alzheimer's disease.Semantic proximity Read ↗

GSTM1 Null Genotype and GSTP1 Ile105Val Polymorphism Are Associated with Alzheimer's Disease: a Meta-Analysis.Semantic proximity Read ↗

GSTM1 null genotype as risk factor for late-onset Alzheimer's disease in Italian patients.Semantic proximity Read ↗

Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population.Semantic proximity Read ↗

Glutathione S-transferase variants increase susceptibility for late-onset Alzheimer's disease: association study and relationship with apolipoprotein E epsilon4 allele.Semantic proximity Read ↗

Glutathione S-transferase P1 *C allelic variant increases susceptibility for late-onset Alzheimer disease: association study and relationship with apolipoprotein E epsilon4 allele.Semantic proximity Read ↗

Glutathione S-transferase M1 (GSTM1) polymorphism is associated with atopic dermatitis susceptibility in a Korean population.Semantic proximity Read ↗

Determination of glutathione S-transferase mu and theta polymorphisms in neurological disease.Semantic proximity Read ↗

Association of GSTT1 and GSTM1 polymorphisms in South Indian Epilepsy Patients.Semantic proximity Read ↗

Human glutathione s-transferase enzyme gene variations and risk of multiple sclerosis in Iranian population cohort.Semantic proximity Read ↗

Distribution of glutathione S-transferase T1 and M1 genes polymorphisms in North East Indians: a potential report.Semantic proximity Read ↗

Glutathione S-transferase P1 and T1 gene polymorphisms predict longitudinal course and age at onset of Alzheimer disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.