Article
Netrin-1 is required for efficient neural tube closure.
Developmental neurobiology - 1 Feb 2013
Kee Nigel, Wilson Nicole, Key Brian, Cooper Helen M
Abstract excerpt
During neural tube formation, neural plate cells migrate from the lateral aspects of the dorsal surface towards the midline. Elevation of the lateral regions of the neural plate produces the neural folds which then migrate to the midline where they fuse at their dorsal tips, generating a closed neural tube comprising an apicobasally polarized neuroepithelium. Our previous study identified a novel role for the...
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