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Article

Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila.

Nature communications - 17 Nov 2017

Perez-Mockus Gantas, Mazouni Khalil, Roca Vanessa, Corradi Giulia, Conte Vito, Schweisguth François

Abstract excerpt

Embryo-scale morphogenesis arises from patterned mechanical forces. During Drosophila gastrulation, actomyosin contractility drives apical constriction in ventral cells, leading to furrow formation and mesoderm invagination. It remains unclear whether and how mechanical properties of the ectoderm influence this process. Here, we show that Neuralized (Neur), an E3 ubiquitin ligase active in the mesoderm, regulates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29150614
DOI: 10.1038/s41467-017-01482-8
PMCID: PMC5693868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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